understanding HLA haplotypes
Understanding haplotypes is a key part of healing from mold and CIRS.
12-3-52B Multisusceptible
The 12-3-52B haplotype is one of the multisusceptible types. Individuals with this haplotype may have a harder time clearing biotoxins toxins from the body because their immune system may not recognize them properly.
These may include, but are not limited to:
These may include, but are not limited to:
- Mold
- Actinobacteria
- Endotoxins (from Gram-negative bacteria)
- Cyanobacteria (from blue-green algae)
- Dinoflagellates (toxic plankton)
- Pfisteria (algae-related toxin)
- Ciguatera (toxin from reef fish)
- Lyme
- Brown recluse spider venom
- Rattlesnake venom
Immune Response Insight:
This genetic profile may reduce your body’s ability to recognize and clear out these toxins effectively. As a result, exposures that wouldn’t impact others may lead to chronic symptoms in those with this haplotype.
Worth Noting:
While this haplotype is sometimes referred to as one of the “dreaded” genes, many people with 12-3-52B respond well to treatment once their unique needs are addressed.
This genetic profile may reduce your body’s ability to recognize and clear out these toxins effectively. As a result, exposures that wouldn’t impact others may lead to chronic symptoms in those with this haplotype.
Worth Noting:
While this haplotype is sometimes referred to as one of the “dreaded” genes, many people with 12-3-52B respond well to treatment once their unique needs are addressed.
** Your HLA genes are part of your immune system’s ability to recognize and respond to threats. But certain haplotypes are essentially “faulty”—they don’t help your body recognize or clear biotoxins the way most people’s do. This sets off the innate immune response, which triggers inflammation, but the adaptive immune system never kicks in to finish the job. The result? Toxins get trapped in the body, inflammation floods your system, and the immune response never shuts off. This is what can lead to CIRS—Chronic Inflammatory Response Syndrome. *This information is for educational purposes only and not a substitute for medical care. **
