understanding HLA haplotypes
Understanding haplotypes is a key part of healing from mold and CIRS.
13-3-52A/B: Multisusceptible
The 13-3-52A haplotype has been statistically linked to increased susceptibility to a variety of biotoxins. These may include:
- Mold
- Endotoxins and Actinobacteria
- Lyme disease
- Ciguatera (toxin from certain fish)
- Pfiesteria (toxic algae)
- Dinoflagellates (marine plankton)
- Cyanobacteria (blue-green algae)
- Northern recluse spider venom
- Rattlesnake venom
What This Means for You:
This genetic profile may influence how effectively your immune system can identify and remove these toxins. People with multisusceptible haplotypes may find that their bodies hold on to biotoxins longer than others, increasing the likelihood of chronic symptoms following exposure.
Originally considered benign, this haplotype was later reclassified by Dr. Shoemaker as multisusceptible.
Good News:
Even though it’s often included among the so-called “dreaded” genes, many individuals with 13-3-52A improve significantly with the right protocols and environmental changes.
This genetic profile may influence how effectively your immune system can identify and remove these toxins. People with multisusceptible haplotypes may find that their bodies hold on to biotoxins longer than others, increasing the likelihood of chronic symptoms following exposure.
Originally considered benign, this haplotype was later reclassified by Dr. Shoemaker as multisusceptible.
Good News:
Even though it’s often included among the so-called “dreaded” genes, many individuals with 13-3-52A improve significantly with the right protocols and environmental changes.
** Your HLA genes are part of your immune system’s ability to recognize and respond to threats. But certain haplotypes are essentially “faulty”—they don’t help your body recognize or clear biotoxins the way most people’s do. This sets off the innate immune response, which triggers inflammation, but the adaptive immune system never kicks in to finish the job. The result? Toxins get trapped in the body, inflammation floods your system, and the immune response never shuts off. This is what can lead to CIRS—Chronic Inflammatory Response Syndrome. *This information is for educational purposes only and not a substitute for medical care. **
